Tocopheryl acetate, also known as vitamin E acetate, is a common vitamin supplement. It is the ester of acetic acid and tocopherol (vitamin E). It is often used in dermatological products such as skin creams. Tocopheryl acetate is not oxidized and can penetrate through the skin to the living cells, where about 5% is converted to free tocopherol and provides beneficial antioxidant effects.As an antioxidant, vitamin E acts as a peroxyl radical scavenger, preventing the propagation of free radicals in tissues, by reacting with them to form a tocopheryl radical, which will then be reduced by a hydrogen donor (such as vitamin C) and thus return to its reduced state. · As an enzymatic activity regulator, for instance, protein kinase C (PKC), which plays a role in smooth muscle growth, can be inhibited by α-tocopherol. · Vitamin E also has an effect on gene expression. Macrophages rich in cholesterol are found in the atherogenetic tissue. · Vitamin E also plays a role in neurological functions,and inhibition of platelet aggregation · Vitamin E also protects lipids and prevents the oxidation of polyunsaturated fatty acids.